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Activation of caspases-8 and -10 by FLIP(L)
The first step in caspase activation is transition of the latent zymogen to an active form. For the initiator caspases, this occurs through dimerization of monomeric zymogens at an activating complex. Recent studies have suggested that FLIP(L) [FLICE-like inhibitory protein, long form; FLICE is FADD...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133822/ https://ncbi.nlm.nih.gov/pubmed/15209560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040809 |
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