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Activation of caspases-8 and -10 by FLIP(L)

The first step in caspase activation is transition of the latent zymogen to an active form. For the initiator caspases, this occurs through dimerization of monomeric zymogens at an activating complex. Recent studies have suggested that FLIP(L) [FLICE-like inhibitory protein, long form; FLICE is FADD...

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Detalhes bibliográficos
Main Authors: Boatright, Kelly M., Deis, Cristina, Denault, Jean-Bernard, Sutherlin, Daniel P., Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133822/
https://ncbi.nlm.nih.gov/pubmed/15209560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040809
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