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Activation of caspases-8 and -10 by FLIP(L)

The first step in caspase activation is transition of the latent zymogen to an active form. For the initiator caspases, this occurs through dimerization of monomeric zymogens at an activating complex. Recent studies have suggested that FLIP(L) [FLICE-like inhibitory protein, long form; FLICE is FADD...

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Autors principals: Boatright, Kelly M., Deis, Cristina, Denault, Jean-Bernard, Sutherlin, Daniel P., Salvesen, Guy S.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133822/
https://ncbi.nlm.nih.gov/pubmed/15209560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040809
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