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Activation of caspases-8 and -10 by FLIP(L)

The first step in caspase activation is transition of the latent zymogen to an active form. For the initiator caspases, this occurs through dimerization of monomeric zymogens at an activating complex. Recent studies have suggested that FLIP(L) [FLICE-like inhibitory protein, long form; FLICE is FADD...

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Détails bibliographiques
Auteurs principaux: Boatright, Kelly M., Deis, Cristina, Denault, Jean-Bernard, Sutherlin, Daniel P., Salvesen, Guy S.
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133822/
https://ncbi.nlm.nih.gov/pubmed/15209560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040809
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