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NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity
Nucleotide-binding, leucine-rich repeat containing X1 (NLRX1) is a mitochondria-located innate immune sensor that inhibits major pro-inflammatory pathways such as type I interferon and nuclear factor-κB signaling. We generated a novel, spontaneous, and rapidly progressing mouse model of multiple scl...
Shranjeno v:
| izdano v: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6762215/ https://ncbi.nlm.nih.gov/pubmed/31525189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000451 |
| Oznake: |
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