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Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes

Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is required for the survival and activation of memory CD8(+)T cells, natural killer (NK) cells, innate lymphoid cells, macrophages and dendritic cells. IL-15 is implicated in the pathogenesis of various autoimmune diseases such as rheumatoid...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Bobbala, Diwakar, Mayhue, Marian, Menendez, Alfredo, Ilangumaran, Subburaj, Ramanathan, Sheela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520411/
https://ncbi.nlm.nih.gov/pubmed/26853723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.102
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