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IL-15 trans-presentation regulates homeostasis of CD4(+) T lymphocytes

Interleukin-15 (IL-15) is essential for the survival of memory CD8(+) and CD4(+) T cell subsets, and natural killer and natural killer T cells. Here, we describe a hitherto unreported role of IL-15 in regulating homoeostasis of naive CD4(+) T cells. Adoptive transfer of splenocytes from non-obese di...

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Detalhes bibliográficos
Main Authors: Chen, Xi-Lin, Bobbala, Diwakar, Cepero Donates, Yuneivy, Mayhue, Marian, Ilangumaran, Subburaj, Ramanathan, Sheela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085515/
https://ncbi.nlm.nih.gov/pubmed/24658435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.13
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