GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes

Long-term survival of T lymphocytes in quiescent state is essential to maintain their cell numbers in secondary lymphoid organs. In mice and in rats, the loss of functional GTPase of the immune associated nucleotide binding protein 5 (GIMAP5) causes peripheral T lymphopenia due to spontaneous death...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Chen, Xi-Lin, Serrano, Daniel, Mayhue, Marian, Hoebe, Kasper, Ilangumaran, Subburaj, Ramanathan, Sheela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595448/
https://ncbi.nlm.nih.gov/pubmed/26440416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139019
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