TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)

GTPase of the immune associated nucleotide binding protein (GIMAP) family of proteins are expressed essentially in cells of the hematopoietic system. Mutation in the founding member of this gene family, Gimap5, results in the lymphopenic phenotype in Bio-Breeding diabetes prone rats. In mice, deleti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Xi-Lin, Serrano, Daniel, Ghobadi, Farnaz, Mayhue, Marian, Hoebe, Kasper, Ilangumaran, Subburaj, Ramanathan, Sheela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811415/
https://ncbi.nlm.nih.gov/pubmed/27023180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151837
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