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GTPase of the Immune-Associated Nucleotide Protein 5 Regulates the Lysosomal Calcium Compartment in T Lymphocytes
T lymphocytes from Gimap5(lyp/lyp) rats carrying a recessive mutation in the GTPase of immune-associated protein 5 (Gimap5) gene undergo spontaneous apoptosis. Molecular mechanisms underlying this survival defect are not yet clear. We have shown that Gimap5(lyp/lyp) T lymphocytes display reduced cal...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293772/ https://ncbi.nlm.nih.gov/pubmed/28223986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00094 |
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