NLRC5 elicits antitumor immunity by enhancing processing and presentation of tumor antigens to CD8(+) T lymphocytes

Cancers can escape immunesurveillance by diminishing the expression of MHC class-I molecules (MHC-I) and components of the antigen-processing machinery (APM). Developing new approaches to reverse these defects could boost the efforts to restore antitumor immunity. Recent studies have shown that the...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Rodriguez, Galaxia M., Bobbala, Diwakar, Serrano, Daniel, Mayhue, Marian, Champagne, Audrey, Saucier, Caroline, Steimle, Viktor, Kufer, Thomas A., Menendez, Alfredo, Ramanathan, Sheela, Ilangumaran, Subburaj
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938303/
https://ncbi.nlm.nih.gov/pubmed/27471621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1151593
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