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GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes

Long-term survival of T lymphocytes in quiescent state is essential to maintain their cell numbers in secondary lymphoid organs. In mice and in rats, the loss of functional GTPase of the immune associated nucleotide binding protein 5 (GIMAP5) causes peripheral T lymphopenia due to spontaneous death...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Chen, Xi-Lin, Serrano, Daniel, Mayhue, Marian, Hoebe, Kasper, Ilangumaran, Subburaj, Ramanathan, Sheela
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595448/
https://ncbi.nlm.nih.gov/pubmed/26440416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139019
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