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GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes

Long-term survival of T lymphocytes in quiescent state is essential to maintain their cell numbers in secondary lymphoid organs. In mice and in rats, the loss of functional GTPase of the immune associated nucleotide binding protein 5 (GIMAP5) causes peripheral T lymphopenia due to spontaneous death...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Chen, Xi-Lin, Serrano, Daniel, Mayhue, Marian, Hoebe, Kasper, Ilangumaran, Subburaj, Ramanathan, Sheela
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595448/
https://ncbi.nlm.nih.gov/pubmed/26440416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139019
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