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Mature DIABLO/Smac Is Produced by the IMP Protease Complex on the Mitochondrial Inner Membrane
DIABLO/Smac is a mitochondrial protein that can promote apoptosis by promoting the release and activation of caspases. To do so, DIABLO/Smac must first be processed by a mitochondrial protease and then released into the cytosol, and we show this in an intact cellular system. We propose that the prec...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142436/ https://ncbi.nlm.nih.gov/pubmed/15814844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1086 |
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