A Dimeric Smac/Diablo Peptide Directly Relieves Caspase-3 Inhibition by XIAP: Dynamic and Cooperative Regulation of XIAP by Smac/Diablo

Caspase activation, the executing event of apoptosis, is under deliberate regulation. IAP proteins inhibit caspase activity whereas Smac/Diablo antagonizes IAP. XIAP, a ubiquitous IAP, can inhibit both caspase-9, the initiator caspase of the mitochondrial apoptotic pathway, and the downstream effect...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Gao, Zhonghua, Tian, Yuan, Wang, Junru, Yin, Qian, Wu, Hao, Li, Yue-Ming, Jiang, Xuejun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202417/
https://ncbi.nlm.nih.gov/pubmed/17724022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705258200
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items