טוען...
The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo
ARTS (Sept4_i2) is a pro-apoptotic tumor suppressor protein that functions as an antagonist of X-linked IAP (XIAP) to promote apoptosis. It is generally thought that mitochondrial outer membrane permeabilization (MOMP) occurs before activation of caspases and is required for it. Here, we show that A...
שמור ב:
| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263492/ https://ncbi.nlm.nih.gov/pubmed/21869827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.112 |
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