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IAP proteins: sticking it to Smac
Dogma has it that suppression of the programmed cell death pathway by the IAP (inhibitor of apoptosis) proteins is achieved by their direct enzymic inhibition of the chief executioners of the apoptotic process, the caspases. In turn, the IAPs themselves can be neutralized by Smac/DIABLO (second mito...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134701/ https://ncbi.nlm.nih.gov/pubmed/15588250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041800 |
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