Disturbed balance of expression between XIAP and Smac/DIABLO during tumour progression in renal cell carcinomas

Dysregulation of apoptosis plays an important role in tumour progression and resistance to chemotherapy. The X-linked inhibitor of apoptosis (XIAP) is considered to be the most potent caspase inhibitor of all known inhibitor of apoptosis-family members. Only recently, an antagonist of XIAP has been...

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Main Authors: Yan, Y, Mahotka, C, Heikaus, S, Shibata, T, Wethkamp, N, Liebmann, J, Suschek, C V, Guo, Y, Gabbert, H E, Gerharz, C D, Ramp, U
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2004
נושאים:
Molecular and Cellular Pathology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409908/
https://ncbi.nlm.nih.gov/pubmed/15328523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602127
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