Generation and Characterization of Smac/DIABLO-Deficient Mice

The mitochondrial proapoptotic protein Smac/DIABLO has recently been shown to potentiate apoptosis by counteracting the antiapoptotic function of the inhibitor of apoptosis proteins (IAPs). In response to apoptotic stimuli, Smac is released into the cytosol and promotes caspase activation by binding...

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Bibliografiske detaljer
Main Authors: Okada, Hitoshi, Suh, Woong-Kyung, Jin, Jianping, Woo, Minna, Du, Chunying, Elia, Andrew, Duncan, Gordon S., Wakeham, Andrew, Itie, Annick, Lowe, Scott W., Wang, Xiaodong, Mak, Tak W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133802/
https://ncbi.nlm.nih.gov/pubmed/11971981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.10.3509-3517.2002
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