Generation and Characterization of Smac/DIABLO-Deficient Mice
The mitochondrial proapoptotic protein Smac/DIABLO has recently been shown to potentiate apoptosis by counteracting the antiapoptotic function of the inhibitor of apoptosis proteins (IAPs). In response to apoptotic stimuli, Smac is released into the cytosol and promotes caspase activation by binding...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11971981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.10.3509-3517.2002 |
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