Generation and Characterization of Smac/DIABLO-Deficient Mice

The mitochondrial proapoptotic protein Smac/DIABLO has recently been shown to potentiate apoptosis by counteracting the antiapoptotic function of the inhibitor of apoptosis proteins (IAPs). In response to apoptotic stimuli, Smac is released into the cytosol and promotes caspase activation by binding...

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מידע ביבליוגרפי
Main Authors: Okada, Hitoshi, Suh, Woong-Kyung, Jin, Jianping, Woo, Minna, Du, Chunying, Elia, Andrew, Duncan, Gordon S., Wakeham, Andrew, Itie, Annick, Lowe, Scott W., Wang, Xiaodong, Mak, Tak W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2002
נושאים:
Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC133802/
https://ncbi.nlm.nih.gov/pubmed/11971981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.10.3509-3517.2002
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