Generation and Characterization of Smac/DIABLO-Deficient Mice

The mitochondrial proapoptotic protein Smac/DIABLO has recently been shown to potentiate apoptosis by counteracting the antiapoptotic function of the inhibitor of apoptosis proteins (IAPs). In response to apoptotic stimuli, Smac is released into the cytosol and promotes caspase activation by binding...

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Detalhes bibliográficos
Main Authors: Okada, Hitoshi, Suh, Woong-Kyung, Jin, Jianping, Woo, Minna, Du, Chunying, Elia, Andrew, Duncan, Gordon S., Wakeham, Andrew, Itie, Annick, Lowe, Scott W., Wang, Xiaodong, Mak, Tak W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133802/
https://ncbi.nlm.nih.gov/pubmed/11971981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.10.3509-3517.2002
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