Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP

Eitemau Tebyg

• The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites
  gan: Silke, John, et al.
  Cyhoeddwyd: (2002)
• Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9
  gan: Ekert, Paul G., et al.
  Cyhoeddwyd: (2001)
• Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance
  gan: Silke, John, et al.
  Cyhoeddwyd: (2005)
• Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors.
  gan: Ekert, P G, et al.
  Cyhoeddwyd: (1999)
• Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
  gan: Allam, Ramanjaneyulu, et al.
  Cyhoeddwyd: (2014)