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Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance

Inhibitor of apoptosis (IAP) proteins, which bind to caspases via their baculoviral IAP repeat domains, also bear RING domains that enable them to promote ubiquitylation of themselves and other interacting proteins. Here we show that the RING domain of cIAP1 allows it to bind directly to the RING of...

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Bibliografske podrobnosti
Main Authors: Silke, John, Kratina, Tobias, Chu, Diep, Ekert, Paul G., Day, Catherine L., Pakusch, Miha, Huang, David C. S., Vaux, David L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283416/
https://ncbi.nlm.nih.gov/pubmed/16263936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502828102
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