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Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance
Inhibitor of apoptosis (IAP) proteins, which bind to caspases via their baculoviral IAP repeat domains, also bear RING domains that enable them to promote ubiquitylation of themselves and other interacting proteins. Here we show that the RING domain of cIAP1 allows it to bind directly to the RING of...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283416/ https://ncbi.nlm.nih.gov/pubmed/16263936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502828102 |
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