Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance

Inhibitor of apoptosis (IAP) proteins, which bind to caspases via their baculoviral IAP repeat domains, also bear RING domains that enable them to promote ubiquitylation of themselves and other interacting proteins. Here we show that the RING domain of cIAP1 allows it to bind directly to the RING of...

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Detalhes bibliográficos
Main Authors: Silke, John, Kratina, Tobias, Chu, Diep, Ekert, Paul G., Day, Catherine L., Pakusch, Miha, Huang, David C. S., Vaux, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283416/
https://ncbi.nlm.nih.gov/pubmed/16263936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502828102
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