Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding

Cellular inhibitor of apoptosis (cIAP) proteins, cIAP1 and cIAP2, are important regulators of tumor necrosis factor (TNF) superfamily (SF) signaling and are amplified in a number of tumor types. They are targeted by IAP antagonist compounds that are undergoing clinical trials. IAP antagonist compoun...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Feltham, Rebecca, Moulin, Maryline, Vince, James E., Mace, Peter D., Wong, Wendy Wei-Lynn, Anderton, Holly, Day, Catherine L., Vaux, David L., Silke, John
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2010
الموضوعات:
Signal Transduction
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878517/
https://ncbi.nlm.nih.gov/pubmed/20356846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087635
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة