Life in the balance: how BH3-only proteins induce apoptosis

Por Willis, Simon N, Adams, Jerry M
Publicado em 2005

Immune surveillance of intracranial germ cell tumors

Por Willis, Simon N., Mallozzi, Scott S., O’Connor, Kevin C.
Publicado em 2008

Investigating the Antigen Specificity of Multiple Sclerosis Central Nervous System-Derived Immunoglobulins

Por Willis, Simon N., Stathopoulos, Panos, Chastre, Anne, Compton, Shannon D., Hafler, David A., O’Connor, Kevin C.
Publicado no Front Immunol (2015)

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x(L), but not Bcl-2, until displaced by BH3-only proteins

Por Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., Adams, Jerry M., Huang, David C.S.
Publicado em 2005

Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1

Por Kvansakul, Marc, Wei, Andrew H., Fletcher, Jamie I., Willis, Simon N., Chen, Lin, Roberts, Andrew W., Huang, David C. S., Colman, Peter M.
Publicado em 2010

Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis

Por Lovato, Laura, Willis, Simon N., Rodig, Scott J., Caron, Tyler, Almendinger, Stefany E., Howell, Owain W., Reynolds, Richard, O’Connor, Kevin C., Hafler, David A.
Publicado em 2011

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

Por Willis, Simon N., Tellier, Julie, Liao, Yang, Trezise, Stephanie, Light, Amanda, O’Donnell, Kristy, Garrett-Sinha, Lee Ann, Shi, Wei, Tarlinton, David M., Nutt, Stephen L.
Publicado no Nat Commun (2017)

Protein array–based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis

Por Querol, Luis, Clark, Pamela L., Bailey, Mary A., Cotsapas, Chris, Cross, Anne H., Hafler, David A., Kleinstein, Steven H., Lee, Jae-Yun, Yaari, Gur, Willis, Simon N., O'Connor, Kevin C.
Publicado em 2013

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

Por Lee, Erinna F., Czabotar, Peter E., van Delft, Mark F., Michalak, Ewa M., Boyle, Michelle J., Willis, Simon N., Puthalakath, Hamsa, Bouillet, Philippe, Colman, Peter M., Huang, David C.S., Fairlie, W. Douglas
Publicado em 2008

Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

Por Willis, Simon N., Stadelmann, Christine, Rodig, Scott J., Caron, Tyler, Gattenloehner, Stefan, Mallozzi, Scott S., Roughan, Jill E., Almendinger, Stefany E., Blewett, Megan M., Brück, Wolfgang, Hafler, David A., O’Connor, Kevin C.
Publicado em 2009

Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin

Por Obermeier, Birgit, Lovato, Laura, Mentele, Reinhard, Brück, Wolfgang, Forne, Ignasi, Imhof, Axel, Lottspeich, Friedrich, Turk, Katherine W., Willis, Simon N., Wekerle, Hartmut, Hohlfeld, Reinhard, Hafler, David A., O'Connor, Kevin C., Dornmair, Klaus
Publicado em 2011

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Por van Delft, Mark F., Wei, Andrew H., Mason, Kylie D., Vandenberg, Cassandra J., Chen, Lin, Czabotar, Peter E., Willis, Simon N., Scott, Clare L., Day, Catherine L., Cory, Suzanne, Adams, Jerry M., Roberts, Andrew W., Huang, David C.S.
Publicado em 2006

Autoantibodies Produced at the Site of Tissue Damage Provide Evidence of Humoral Autoimmunity in Inclusion Body Myositis

Por Ray, Arundhati, Amato, Anthony A., Bradshaw, Elizabeth M., Felice, Kevin J., DiCapua, Daniel B., Goldstein, Jonathan M., Lundberg, Ingrid E., Nowak, Richard J., Ploegh, Hidde L., Spooner, Eric, Wu, Qian, Willis, Simon N., O’Connor, Kevin C.
Publicado em 2012

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

Por Carotta, Sebastian, Willis, Simon N., Hasbold, Jhagvaral, Inouye, Michael, Pang, Swee Heng Milon, Emslie, Dianne, Light, Amanda, Chopin, Michael, Shi, Wei, Wang, Hongsheng, Morse, Herbert C., Tarlinton, David M., Corcoran, Lynn M., Hodgkin, Philip D., Nutt, Stephen L.
Publicado em 2014

Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

Por Huntington, Nicholas D, Puthalakath, Hamsa, Gunn, Priscilla, Naik, Edwina, Michalak, Ewa M, Smyth, Mark J, Tabarias, Hyacinth, Degli-Esposti, Mariapia A, Dewson, Grant, Willis, Simon N, Motoyama, Noboru, Huang, David C S, Nutt, Stephen L, Tarlinton, David M, Strasser, Andreas
Publicado em 2007

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins

Por Trezise, Stephanie, Karnowski, Alexander, Fedele, Pasquale L., Mithraprabhu, Sridurga, Liao, Yang, D’Costa, Kathy, Kueh, Andrew J., Hardy, Matthew P., Owczarek, Catherine M., Herold, Marco J., Spencer, Andrew, Shi, Wei, Willis, Simon N., Nutt, Stephen L., Corcoran, Lynn M.
Publicado no Int J Mol Sci (2018)

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

Por de Valle, Elisha, Grigoriadis, George, O’Reilly, Lorraine A., Willis, Simon N., Maxwell, Mhairi J., Corcoran, Lynn M., Tsantikos, Evelyn, Cornish, Jasper K.S., Fairfax, Kirsten A., Vasanthakumar, Ajithkumar, Febbraio, Mark A., Hibbs, Margaret L., Pellegrini, Marc, Banerjee, Ashish, Hodgkin, Philip D., Kallies, Axel, Mackay, Fabienne, Strasser, Andreas, Gerondakis, Steve, Gugasyan, Raffi
Publicado no J Exp Med (2016)

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

Por Almeida, Francisca F., Tognarelli, Sara, Marçais, Antoine, Kueh, Andrew J., Friede, Miriam E., Liao, Yang, Willis, Simon N., Luong, Kylie, Faure, Fabrice, Mercier, Francois E., Galluso, Justine, Firth, Matthew, Narni-Mancinelli, Emilie, Rais, Bushra, Scadden, David T., Spallotta, Francesco, Weil, Sandra, Giannattasio, Ariane, Kalensee, Franziska, Zöller, Tobias, Huntington, Nicholas D., Schleicher, Ulrike, Chiocchetti, Andreas G., Ugolini, Sophie, Herold, Marco J., Shi, Wei, Koch, Joachim, Steinle, Alexander, Vivier, Eric, Walzer, Thierry, Belz, Gabrielle T., Ullrich, Evelyn
Publicado no Oncoimmunology (2018)