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Life in the balance: how BH3-only proteins induce apoptosis

BH3-only members of the Bcl-2 intracellular protein family, which include Bim, Bmf, Bik, Bad, Bid, Puma, Noxa and Hrk, mediate many developmentally programmed and induced cytotoxic signals. They have key roles in development, tissue homeostasis, immunity and tumor suppression, and compounds mimickin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Willis, Simon N, Adams, Jerry M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930980/
https://ncbi.nlm.nih.gov/pubmed/16243507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2005.10.001
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