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Life in the balance: how BH3-only proteins induce apoptosis

BH3-only members of the Bcl-2 intracellular protein family, which include Bim, Bmf, Bik, Bad, Bid, Puma, Noxa and Hrk, mediate many developmentally programmed and induced cytotoxic signals. They have key roles in development, tissue homeostasis, immunity and tumor suppression, and compounds mimickin...

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Detalhes bibliográficos
Main Authors: Willis, Simon N, Adams, Jerry M
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930980/
https://ncbi.nlm.nih.gov/pubmed/16243507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2005.10.001
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