Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin

We investigated the overlap shared between the immunoglobulin (Ig) proteome of the cerebrospinal fluid (CSF) and the B cell Ig-transcriptome of CSF and the central nervous system (CNS) tissue of three patients with multiple sclerosis. We determined the IgG-proteomes of CSF by mass spectrometry, and...

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Detalhes bibliográficos
Main Authors: Obermeier, Birgit, Lovato, Laura, Mentele, Reinhard, Brück, Wolfgang, Forne, Ignasi, Imhof, Axel, Lottspeich, Friedrich, Turk, Katherine W., Willis, Simon N., Wekerle, Hartmut, Hohlfeld, Reinhard, Hafler, David A., O'Connor, Kevin C., Dornmair, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090654/
https://ncbi.nlm.nih.gov/pubmed/21353315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2011.01.010
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