Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins

Oligoclonal Ig bands (OCBs) of the cerebrospinal fluid are a hallmark of multiple sclerosis (MS), a disabling inflammatory disease of the central nervous system (CNS). OCBs are locally produced by clonally expanded antigen-experienced B cells and therefore are believed to hold an important clue to t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Brändle, Simone M., Obermeier, Birgit, Senel, Makbule, Bruder, Jessica, Mentele, Reinhard, Khademi, Mohsen, Olsson, Tomas, Tumani, Hayrettin, Kristoferitsch, Wolfgang, Lottspeich, Friedrich, Wekerle, Hartmut, Hohlfeld, Reinhard, Dornmair, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948369/
https://ncbi.nlm.nih.gov/pubmed/27325759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522730113
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