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Target Specificity of an Autoreactive Pathogenic Human γδ-T Cell Receptor in Myositis
In polymyositis and inclusion body myositis, muscle fibers are surrounded and invaded by CD8-positive cytotoxic T cells expressing the αβ-T cell receptor (αβ-TCR) for antigen. In a rare variant of myositis, muscle fibers are similarly attacked by CD8-negative T cells expressing the γδ-TCR (γδ-T cell...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375522/ https://ncbi.nlm.nih.gov/pubmed/22549773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356709 |
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