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Reconstitution of paired T cell receptor α- and β-chains from microdissected single cells of human inflammatory tissues
We describe a strategy to “revive” putatively pathogenic T cells from frozen specimens of human inflammatory target organs. To distinguish pathogenic from irrelevant bystander T cells, we focused on cells that were (i) clonally expanded and (ii) in direct morphological contact with a target cell. Us...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567696/ https://ncbi.nlm.nih.gov/pubmed/16882720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604247103 |
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