Reconstitution of paired T cell receptor α- and β-chains from microdissected single cells of human inflammatory tissues

We describe a strategy to “revive” putatively pathogenic T cells from frozen specimens of human inflammatory target organs. To distinguish pathogenic from irrelevant bystander T cells, we focused on cells that were (i) clonally expanded and (ii) in direct morphological contact with a target cell. Us...

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Bibliografiska uppgifter
Huvudupphovsmän: Seitz, Sabine, Schneider, Christian K., Malotka, Joachim, Nong, Xiao, Engel, Andrew G., Wekerle, Hartmut, Hohlfeld, Reinhard, Dornmair, Klaus
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567696/
https://ncbi.nlm.nih.gov/pubmed/16882720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604247103
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