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MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication

Successful replication and transmission of large DNA viruses such as the cytomegaloviruses (CMV) family of viruses depends on the ability to interfere with multiple aspects of the host immune response. Apoptosis functions as a host innate defence mechanism against viral infection, and the capacity t...

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Detalhes bibliográficos
Main Authors: Fleming, Peter, Kvansakul, Marc, Voigt, Valentina, Kile, Benjamin T., Kluck, Ruth M., Huang, David C. S., Degli-Esposti, Mariapia A., Andoniou, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585157/
https://ncbi.nlm.nih.gov/pubmed/23468630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003192
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