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Bid binding to negatively charged phospholipids may not be required for its pro-apoptotic activity in vivo
Bid is a ubiquitous pro-apoptotic member of the Bcl-2 family that has been involved in a variety of pathways of cell death. Unique among pro-apoptotic proteins, Bid is activated after cleavage by the apical caspases of the extrinsic pathway; subsequently it moves to mitochondria, where it promotes t...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822702/ https://ncbi.nlm.nih.gov/pubmed/19463967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.05.003 |
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