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Stepwise activation of the pro-apoptotic protein Bid at mitochondrial membranes
Caspase-8-cleaved Bid (cBid) associates with mitochondria and promotes the activation of BAX, leading to mitochondria outer membrane permeabilization (MOMP) and apoptosis. However, current structural models of cBid are largely based on studies using membrane vesicles and detergent micelles. Here we...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8184993/ https://ncbi.nlm.nih.gov/pubmed/33462413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00716-5 |
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