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The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites
BACKGROUND: Following cleavage by caspase 8, the C-terminus of Bid translocates from the cytosol to the mitochondria that is dependent upon structures formed by the mitochondrial-specific lipid cardiolipin. Once associated with mitochondria, truncated Bid (tBid) causes the potent release of cytochro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC59886/ https://ncbi.nlm.nih.gov/pubmed/11716782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-2-22 |
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