The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites
BACKGROUND: Following cleavage by caspase 8, the C-terminus of Bid translocates from the cytosol to the mitochondria that is dependent upon structures formed by the mitochondrial-specific lipid cardiolipin. Once associated with mitochondria, truncated Bid (tBid) causes the potent release of cytochro...
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| Publicado no: | BMC Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11716782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-2-22 |
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