Chemokines as Molecular Targets for Therapeutic Intervention

Por Howard, O. M. Zack, Oppenheim, Joost J., Wang, Ji Ming
Publicado no J Clin Immunol (1999)

Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking

Por Chen, Xin, Murakami, Takaya, Oppenheim, Joost J., Howard, O. M. Zack
Publicado em 2005

Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells

Por Kopf, Heather, de la Rosa, Gonzalo M., Howard, O.M.Zack, Chen, Xin
Publicado em 2007

In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+) Foxp3(+) Regulatory T cells in vivo

Por Zhou, Qiong, Hu, Ya, Howard, O.M. Zack, Oppenheim, Joost J., Chen, Xin
Publicado em 2013

Alarmin-induced cell migration

Por Yang, De, Wei, Feng, Tewary, Poonam, Howard, O. M. Zack, Oppenheim, Joost J.
Publicado no Eur J Immunol (2013)

Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN

Por Gao, Ping, Wange, Ronald L., Zhang, Ning, Oppenheim, Joost J., Howard, O. M. Zack
Publicado em 2005

TNFR2 is critical for the stabilization of the CD4(+)FoxP3(+) regulatory T cell phenotype in the inflammatory environment

Por Chen, Xin, Wu, Xueqing, Zhou, Qiong, Howard, O.M. Zack, Netea, Mihai G., Oppenheim, Joost J.
Publicado em 2012

Expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor infiltrating T regulatory cells

Por Chen, Xin, Subleski, Jeffrey J., Kopf, Heather, Howard, O.M.Zack, Männel, Daniela N., Oppenheim, Joost J.
Publicado em 2008

Co-expression of TNFR2 and CD25 identifies more of the functional CD4(+)FoxP3(+) regulatory T cells in human peripheral blood

Por Chen, Xin, Subleski, Jeffrey J., Hamano, Ryoko, Howard, O.M. Zack, Wiltrout, Robert H., Oppenheim, Joost J.
Publicado em 2010

Expression of Costimulatory TNFR2 Induces Resistance of CD4(+)FoxP3(−) Conventional T Cells to Suppression by CD4(+) FoxP3(+) Regulatory T Cells

Por Chen, Xin, Hamano, Ryoko, Subleski, Jeffrey J., Hurwitz, Arthur A., Howard, O. M. Zack, Oppenheim, Joost J.
Publicado no J Immunol (2010)

IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells

Por Chen, Xin, Willette-Brown, Jami, Wu, Xueqiang, Hu, Ya, Howard, O. M. Zack, Hu, Yinling, Oppenheim, Joost J.
Publicado no FASEB J (2015)

Enhanced Immunostimulatory Effects of DNA-Encapsulated Peptide Hydrogels

Por Medina, Scott H., Li, Sandra, Howard, O.M. Zack, Dunlap, Micah, Trivett, Anna, Schneider, Joel P., Oppenheim, Joost J.
Publicado no Biomaterials (2015)

Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate

Por Howard, O. M. Zack, Dong, Hui Fang, Su, Shao Bo, Caspi, Rachel R., Chen, Xin, Plotz, Paul, Oppenheim, Joost J.
Publicado em 2005

Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation

Por Malik, Mariam, Jividen, Kasey, Padmakumar, V. C., Cataisson, Christophe, Li, Luowei, Lee, Jessica, Howard, O. M. Zack, Yuspa, Stuart H.
Publicado em 2012

Shikonin, a Component of Chinese Herbal Medicine, Inhibits Chemokine Receptor Function and Suppresses Human Immunodeficiency Virus Type 1

Por Chen, Xin, Yang, Lu, Zhang, Ning, Turpin, Jim A., Buckheit, Robert W., Osterling, Clay, Oppenheim, Joost J., Howard, O. M. Zack
Publicado em 2003

The alarmin HMGN1 contributes to anti-tumor immunity and is a potent immunoadjuvant

Por Wei, Feng, Yang, De, Tewary, Poonam, Li, Yana, Li, Sandra, Chen, Xin, Howard, O. M. Zack, Bustin, Michael, Oppenheim, Joost J.
Publicado no Cancer Res (2014)

Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation

Por Huang, Jian, Chen, Keqiang, Huang, Jiaqiang, Gong, Wanghua, Dunlop, Nancy M., Howard, O.M.Zack, Bian, Xiuwu, Gao, Yuqi, Wang, Ji Ming
Publicado em 2009

Painful Pathways Induced by Toll-like Receptor Stimulation of Dorsal Root Ganglion Neurons

Por Qi, Jia, Buzas, Krisztina, Fan, Huiting, Cohen, Jeffrey I., Wang, Kening, Mont, Erik, Klinman, Dennis, Oppenheim, Joost J., Howard, O.M. Zack
Publicado em 2011

Monocyte Chemoattractant Protein-1/CCL2 Produced by Stromal Cells Promotes Lung Metastasis of 4T1 Murine Breast Cancer Cells

Por Yoshimura, Teizo, Howard, O. M. Zack, Ito, Toshihiro, Kuwabara, Masaki, Matsukawa, Akihiro, Chen, Keqiang, Liu, Ying, Liu, Mingyong, Oppenheim, Joost J., Wang, Ji Ming
Publicado em 2013

Identification of Human Neutrophil-derived Cathepsin G and Azurocidin/CAP37 as Chemoattractants for Mononuclear Cells and Neutrophils

Por Chertov, Oleg, Ueda, Hirotsugu, Xu, Luo Ling, Tani, Kenji, Murphy, William J., Wang, Ji Ming, Howard, O.M. Zack, Sayers, Thomas J., Oppenheim, Joost J.
Publicado em 1997