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Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate

We tested the hypothesis that interaction between autoantigens and chemoattractant receptors may be an important step in the development of autoimmunity. The retinal autoantigens S-antigen (S-Ag) and interphotoreceptor retinoid binding protein (IRBP) can induce autoimmune uveitis in rodent models. W...

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Detalhes bibliográficos
Main Authors: Howard, O. M. Zack, Dong, Hui Fang, Su, Shao Bo, Caspi, Rachel R., Chen, Xin, Plotz, Paul, Oppenheim, Joost J.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895027/
https://ncbi.nlm.nih.gov/pubmed/15713799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-07-2697
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