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Enhanced Immunostimulatory Effects of DNA-Encapsulated Peptide Hydrogels

DNA that encodes tumor-specific antigens represents potential immunostimulatory agents. However, rapid enzymatic degradation and fragmentation of DNA during administration can result in limited vector expression and, consequently, poor efficacy. These challenges have necessitated the use of novel st...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Medina, Scott H., Li, Sandra, Howard, O.M. Zack, Dunlap, Micah, Trivett, Anna, Schneider, Joel P., Oppenheim, Joost J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735534/
https://ncbi.nlm.nih.gov/pubmed/25890750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.02.125
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