Enhanced Immunostimulatory Effects of DNA-Encapsulated Peptide Hydrogels

DNA that encodes tumor-specific antigens represents potential immunostimulatory agents. However, rapid enzymatic degradation and fragmentation of DNA during administration can result in limited vector expression and, consequently, poor efficacy. These challenges have necessitated the use of novel st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomaterials
Prif Awduron: Medina, Scott H., Li, Sandra, Howard, O.M. Zack, Dunlap, Micah, Trivett, Anna, Schneider, Joel P., Oppenheim, Joost J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735534/
https://ncbi.nlm.nih.gov/pubmed/25890750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.02.125
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