Enhanced Immunostimulatory Effects of DNA-Encapsulated Peptide Hydrogels

DNA that encodes tumor-specific antigens represents potential immunostimulatory agents. However, rapid enzymatic degradation and fragmentation of DNA during administration can result in limited vector expression and, consequently, poor efficacy. These challenges have necessitated the use of novel st...

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Vydáno v:Biomaterials
Hlavní autoři: Medina, Scott H., Li, Sandra, Howard, O.M. Zack, Dunlap, Micah, Trivett, Anna, Schneider, Joel P., Oppenheim, Joost J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735534/
https://ncbi.nlm.nih.gov/pubmed/25890750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.02.125
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