Enhanced Immunostimulatory Effects of DNA-Encapsulated Peptide Hydrogels

DNA that encodes tumor-specific antigens represents potential immunostimulatory agents. However, rapid enzymatic degradation and fragmentation of DNA during administration can result in limited vector expression and, consequently, poor efficacy. These challenges have necessitated the use of novel st...

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Gepubliceerd in:Biomaterials
Hoofdauteurs: Medina, Scott H., Li, Sandra, Howard, O.M. Zack, Dunlap, Micah, Trivett, Anna, Schneider, Joel P., Oppenheim, Joost J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735534/
https://ncbi.nlm.nih.gov/pubmed/25890750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.02.125
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