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TNFR2 is critical for the stabilization of the CD4(+)FoxP3(+) regulatory T cell phenotype in the inflammatory environment
Several lines of evidence indicate the instability of CD4(+)FoxP3(+) regulatory T cells (Tregs). We have therefore investigated means of promoting the stability of Tregs. In this study, we found that the proportion of Tregs in mouse strains deficient in TNFR2 or its ligands was reduced in the thymus...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552130/ https://ncbi.nlm.nih.gov/pubmed/23277487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202659 |
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