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Expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor infiltrating T regulatory cells
TNFR2 is predominantly expressed by a subset of human and mouse CD4+CD25+FoxP3+ Tregs. In this study, we characterized the phenotype and function of TNFR2(+) Tregs in peripheral lymphoid tissues of normal and tumor bearing C57BL/6 mice. We found that TNFR2 was expressed on 30%−40% of peripheral acti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699949/ https://ncbi.nlm.nih.gov/pubmed/18453563 |
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