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Expression of Costimulatory TNFR2 Induces Resistance of CD4(+)FoxP3(−) Conventional T Cells to Suppression by CD4(+) FoxP3(+) Regulatory T Cells

Our previous study showed that TNFR2 is preferentially expressed by CD4(+)FoxP3(+) regulatory T cells (Tregs), and expression of this receptor identified maximally suppressive Tregs. TNFR2 is also expressed by a small fraction of CD4(+)FoxP3(−) conventional T cells (Tconvs) in normal mice, and its e...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Chen, Xin, Hamano, Ryoko, Subleski, Jeffrey J., Hurwitz, Arthur A., Howard, O. M. Zack, Oppenheim, Joost J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314668/
https://ncbi.nlm.nih.gov/pubmed/20525892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903548
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