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TNF by inducing co-stimulatory TNF receptor superfamily members TNFR2, 4-1BB and OX40 augments the number and function of mouse CD4(+)FoxP3(+) regulatory T cells
TNF is a pleiotropic cytokine with intriguing biphasic pro-inflammatory and anti-inflammatory effects. Our previous studies demonstrated that TNF up-regulated FoxP3 expression and activated and expanded CD4(+)FoxP3(+) regulatory T cells (Tregs) by utilizing TNFR2. Further, TNFR2-expressing Tregs exh...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783213/ https://ncbi.nlm.nih.gov/pubmed/21491419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041205 |
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