Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation

Nuclear translocation of cytosolic CLIC4 is an essential feature of its proapoptotic and prodifferentiation functions. Here we demonstrate that CLIC4 is induced concurrently with inducible nitric oxide synthase (iNOS) and S-nitrosylated in proinflammatory peritoneal macrophages. Chemical inhibition...

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Detalhes bibliográficos
Main Authors: Malik, Mariam, Jividen, Kasey, Padmakumar, V. C., Cataisson, Christophe, Li, Luowei, Lee, Jessica, Howard, O. M. Zack, Yuspa, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341024/
https://ncbi.nlm.nih.gov/pubmed/22474389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201351109
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