Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation

Nuclear translocation of cytosolic CLIC4 is an essential feature of its proapoptotic and prodifferentiation functions. Here we demonstrate that CLIC4 is induced concurrently with inducible nitric oxide synthase (iNOS) and S-nitrosylated in proinflammatory peritoneal macrophages. Chemical inhibition...

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Библиографические подробности
Главные авторы: Malik, Mariam, Jividen, Kasey, Padmakumar, V. C., Cataisson, Christophe, Li, Luowei, Lee, Jessica, Howard, O. M. Zack, Yuspa, Stuart H.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341024/
https://ncbi.nlm.nih.gov/pubmed/22474389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201351109
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