Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation

Nuclear translocation of cytosolic CLIC4 is an essential feature of its proapoptotic and prodifferentiation functions. Here we demonstrate that CLIC4 is induced concurrently with inducible nitric oxide synthase (iNOS) and S-nitrosylated in proinflammatory peritoneal macrophages. Chemical inhibition...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Malik, Mariam, Jividen, Kasey, Padmakumar, V. C., Cataisson, Christophe, Li, Luowei, Lee, Jessica, Howard, O. M. Zack, Yuspa, Stuart H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341024/
https://ncbi.nlm.nih.gov/pubmed/22474389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201351109
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