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The alarmin HMGN1 contributes to anti-tumor immunity and is a potent immunoadjuvant

Alarmins are endogenous mediators that are elicited rapidly in response to danger signals, enhancing innate and adaptive immune responses by promoting the recruitment and maturation of antigen-presenting cells (APCs). The nucleosome-binding protein HMGN1 is a potent alarmin that binds TLR4 and induc...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Wei, Feng, Yang, De, Tewary, Poonam, Li, Yana, Li, Sandra, Chen, Xin, Howard, O. M. Zack, Bustin, Michael, Oppenheim, Joost J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309998/
https://ncbi.nlm.nih.gov/pubmed/25205103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2042
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