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Alarmin IL-33 acts as an immunoadjuvant for enhancing antigen-specific cell-mediated immunity resulting in potent anti-tumor immunity

Interleukin 33 (IL-33) has emerged as a cytokine that can exhibit pleiotropic properties. Here we examine IL-33 for its immunoadjuvant effects in an HPV-associated cancer immune therapy model in which cell-mediated immunity is critical for protection. It is known that two biologically active forms o...

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Bibliografiske detaljer
Main Authors: Villarreal, Daniel O., Wise, Megan C., Walters, Jewell N., Reuschel, Emma, Choi, Min Joung, Obeng-Adjei, Nyamekye, Yan, Jian, Morrow, Matthew P., Weiner, David B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130175/
https://ncbi.nlm.nih.gov/pubmed/24448242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2729
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