Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity

High levels of human Telomerase Reverse Transcriptase (hTERT) are detected in over 85% of human cancers. Immunological analysis supports hTERT is a widely applicable target recognized by T cells and can be potentially studied as a broad cancer immune therapeutic, or a unique line of defense against...

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Autori principali: Yan, Jian, Pankhong, Panyupa, Shin, Thomas H., Obeng-Adjei, Nyamekye, Morrow, Matthew P., Walters, Jewell N., Khan, Amir S., Sardesai, Niranjan Y., Weiner, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096936/
https://ncbi.nlm.nih.gov/pubmed/24777680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0001
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